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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASH1L
All Species:
22.73
Human Site:
Y2066
Identified Species:
50
UniProt:
Q9NR48
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR48
NP_060959.2
2969
332790
Y2066
Q
W
K
H
N
Q
L
Y
K
K
P
D
V
P
L
Chimpanzee
Pan troglodytes
XP_513861
2964
332149
Y2061
Q
W
K
H
N
Q
L
Y
K
K
P
D
V
P
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851926
2974
332800
Y2071
Q
W
K
H
N
Q
L
Y
K
K
P
D
V
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99MY8
2958
331289
Y2056
Q
W
K
H
N
Q
L
Y
K
K
P
D
V
P
L
Rat
Rattus norvegicus
NP_001101159
2918
326454
L2038
V
Y
V
D
V
K
P
L
S
G
Y
E
A
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511389
1395
154154
K630
E
T
H
F
S
E
L
K
T
M
P
N
L
Q
P
Chicken
Gallus gallus
XP_422858
2954
330578
Y2052
Q
W
K
H
N
Q
L
Y
K
K
P
D
V
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692254
2962
327377
Y2011
L
W
K
H
D
Q
L
Y
K
R
P
D
V
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW15
2226
246247
S1461
I
D
G
Q
R
M
G
S
D
C
R
F
V
N
H
Honey Bee
Apis mellifera
XP_001122948
2180
246181
K1415
V
R
T
Q
Q
S
I
K
S
G
V
F
I
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784903
3312
363645
P2421
Q
W
V
H
N
K
L
P
S
R
T
Q
A
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
94.1
N.A.
91.7
91.2
N.A.
21.5
79.9
N.A.
40.9
N.A.
26.1
26
N.A.
27.3
Protein Similarity:
100
99.6
N.A.
97
N.A.
95.3
94.4
N.A.
31.8
89.2
N.A.
53
N.A.
42.2
43.9
N.A.
43.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
13.3
100
N.A.
80
N.A.
6.6
0
N.A.
40
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
46.6
100
N.A.
93.3
N.A.
6.6
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
0
10
10
0
0
0
10
0
0
55
0
0
0
% D
% Glu:
10
0
0
0
0
10
0
0
0
0
0
10
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
19
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
0
19
0
0
0
0
0
% G
% His:
0
0
10
64
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
55
0
0
19
0
19
55
46
0
0
0
0
10
% K
% Leu:
10
0
0
0
0
0
73
10
0
0
0
0
10
10
55
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
55
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
64
0
0
64
10
% P
% Gln:
55
0
0
19
10
55
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
10
0
0
10
0
0
0
0
19
10
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
0
10
28
0
0
0
0
0
0
% S
% Thr:
0
10
10
0
0
0
0
0
10
0
10
0
0
10
10
% T
% Val:
19
0
19
0
10
0
0
0
0
0
10
0
64
0
0
% V
% Trp:
0
64
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
55
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _